Here is an interesting article which reports on a range of neuroscience research on how people respond to change. The article explores the following conclusions:

• Change is pain. Organizational change is unexpectedly difficult because it provokes sensations of physiological discomfort.
• Behaviorism doesn’t work. Change efforts based on incentive and threat (the carrot and the stick) rarely succeed in the long run.
• Humanism is overrated. In practice, the conventional empathic approach of connection and persuasion doesn’t sufficiently engage people.
• Focus is power. The act of paying attention creates chemical and physical changes in the brain.
• Expectation shapes reality. People’s preconceptions have a significant impact on what they perceive.
• Attention density shapes identity. Repeated, purposeful, and focused attention can lead to long-lasting personal evolution.